Lawrence Livermore National Laboratory



image

Millions of patients worldwide suffer from severe and disabling paralysis resulting from catastrophic neurological disorders (e.g., spinal cord injury, amyotrophic lateral sclerosis, and stroke). In the vast majority of such patients, there is relative preservation of cognitive function despite the inability to control their muscles and limbs. Brain Machine Interfaces (BMI) promise to significantly improve the quality of life of patients with severe motor disabilities. Currently, the lack of an advanced implantable device is a major obstacle in the clinical translation of recent BMI achievements.

In collaboration with academia, we are developing a chronically implantable, high-density, wireless electrocorticography (ECoG) microelectrode array using advanced yet mature technologies and processes developed at LLNL. The micro-ECoG device will be used acutely in human subjects for neurophysiological and behavioral experiments to obtain a reliability assessment of the state-of-the-art ECoG array. This platform technology has broad applications in clinical medicine beyond BMIs, including ambulatory epilepsy telemetry, biofeedback, brain mapping, psychiatric conditions, and movement disorders.