Design and fabrication of organ-on-a-chip systems, tissue engineering, microfluidics, neurobiological systems, wound healing, neural prosthetic devices, microfabrication and MEMS.
K. Jayarathanam, D. Soscia, R. Schramm , S. Sequeira, M. Larsen, J. Castracane. Hyaluronic Acid- Conjugated Nanofiber Scaffolds for Salivary Gland Tissue Engineering. (in preparation).
D. Soscia, S. Sequeira, R. Schramm, K. Jayarathanam, S. Cantara, M. Larsen, J. Castracane. Salivary Gland Cell Differentiation and Organization on Micropatterned PLGA Nanofiber Craters. (2013) Biomaterials. 34(28): 6773-84.
S. Cantara, D. Soscia, S. Sequeira, R. Jean-Gilles, J. Castracane, M. Larsen. Selective Functionalization of Nanofiber Scaffolds to Regulate Salivary Gland Epithelial Cell Proliferation and Apicobasal Polarity. (2012) Biomaterials. 33(33): 8372-82.
S. Sequeira, D. Soscia, B. Oztan, R. Jean-Gilles, A. Gadre, B. Yener, J. Castracane, M. Larsen. The Regulation of Focal Adhesion Complex Formation and Salivary Gland Epithelial Cell Organization by Nanofibrous PLGA Scaffolds. (2012) Biomaterials. 33(11): 3175-86.
R. Jean-Gilles*, D. Soscia*, S. Sequeira, M. Melfi, A. Gadre, J. Castracane, M. Larsen. Novel Modeling Approach to Generate a Polymeric Nanofiber Scaffold for Salivary Gland Cells. (2010) Journal of Nanotechnology in Engineering and Medicine. 1(3). *Co-first authors
D. Soscia, N.A. Raof, Y. Xie, N.C. Cady, A.P. Gadre. Antibiotic-loaded PLGA Nanofibers for Wound Healing Applications. (2010) Advanced Engineering Materials. 12(4): B83-B88.
D. Soscia, S. Sequeira, B. Schramm, K. Jayarathanam, M. Larsen, J. Castracane. Micropatterned PLGA Nanofiber-Lined Crater Arrays for Engineered Salivary Glands. ASME 2010 2nd Global Congress on NanoEngineering for Medicine and Biology, Boston MA, February 4-6th, 2013. (Nominated by session chair to be considered for Best Technical Presentation Award).
D. Soscia, S. Sequeira, S. Cantara, M. Larsen, J. Castracane. Micropatterned PLGA Nanofiber Crater Arrays for Tissue Engineering. Capital Region Commercialization of Life Sciences Innovation Day, Albany NY, June 1st, 2012.
S. Sequeira, D. Soscia, R. Jean-Gilles, S. Peters, M. Melfi, M. Karass, W. Daley, A. Gadre, J. Castracane, M. Larsen. Nanoscale Topography of 3D Artificial Scaffolds Regulates Salivary Gland Epithelial Cell Morphology and Focal Adhesion Complex Formation. Gordon Research Conference: Salivary Glands & Exocrine Biology, Galveston TX, February 6-11th, 2011.
D. Soscia, R. Jean-Gilles, A. Gadre, M. Larsen, J. Castracane. Micropatterned PLGA Nanofibrous Substrates as Scaffolds for Engineered Salivary Glands. TERMIS North America Conference, Orlando FL, December 6th, 2010.
D. Soscia, R. Jean-Gilles, S. Sequeira, A. Gadre, M. Larsen, J. Castracane. Engineering Functioning Salivary Glands Using Electrospun Nanofiber Scaffolds. Symposium on the Convergence of Nanotechnology and Life Science, Albany NY, March 2010.
D. Soscia et al. "Polymeric Support with Nanofeatures for Cell Culture." International Patent PCT/US11/52011. (September 16 2011)
Patterning Stimulus Award, "Design-based Metrology (DBM)," IBM, 2014