Lawrence Livermore National Laboratory



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Postdoctoral Researcher
Center for Micro and Nano Technology
Materials Engineering Division

  • Ph.D., Analytical Chemistry, University of North Carolina, Chapel Hill, 2013
  • B.S., Chemistry ACS Certified, Baylor University, Waco, TX, 2008
Phone: (925) 924-6606
E-mail: belle1@llnl.gov


Research Interests

  • In vivo electrochemical detection: dopamine, oxygen, pH, serotonin, norepinephrine, adenosine, glutamate, fast-scan cyclic voltammetry, amperometry
  • Electrochemical characterization: cyclic voltammetry, electrochemical impedance spectroscopy, differential pulse voltammetry
  • Biological Signals: electrophysiology, fast-scan cyclic voltammetry (instrumentation, application, analysis)


Selected Publications

Belle AM, Wightman, RM. "Monitoring and modulating dopamine release and unit activity in real-time," In Compendium of In Vivo Monitoring in Real-time Molecular Neuroscience. eds. Michael AC, Wilson GS. World Scientific Publishing Co., 2015 (1) p.161-180.

Owesson-White C, Belle AM, Herr NR, Peele JL, Gowrishankar P, Carelli RM, Wightman RM. "Cue-Evoked Dopamine Release Rapidly Modulates D2 Neurons in the Nucleus Accumbens During Motivated Behavior," J Neurosci. 2016 36(22) p.6011-21.

Bucher ES, Fox ME, Kim L, Kirkpatrick DC, Rodeberg NT, Belle AM, Wightman RM. "Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis," J Cereb Blood Flow Metab. 2014 34(7) p.1128-37.

Belle AM, Owesson-White C, Herr NR, Carelli RM, Wightman RM. "Controlled iontophoresis coupled with fast-scan cyclic voltammetry/electrophysiology in awake, freely moving animals" ACS Chem Neurosci. 2013 4(5) p.761-71.

Owesson-White CA, Roitman MF, Sombers LA, Belle AM, Keithley RB, Peele JL, Carelli RM, Wightman RM. "Sources contributing to the average extracellular concentration of dopamine in the nucleus accumbens," J Neurochem. 2012 121 (2) p.252-62.

MHerr NR, Park J, McElligott ZA, Belle AM, Carelli RM, Wightman RM. "In vivo voltammetry monitoring of electrically evoked extracellular norepinephrine in subregions of the bed nucleus of the stria terminalis," J Neurophysiol. 2012 Mar;107(6):1731-7.

Keithley RB, Takmakov P, Bucher ES, Belle AM, Owesson-White CA, Park J, Wightman RM. "Higher sensitivity dopamine measurements with faster-scan cyclic voltammetry," Anal Chem. 2011 83 (9) p.3563-71.

Herr NR, Belle AM, Daniel KB, Carelli RM, Wightman RM. Probing presynaptic regulation of extracellular dopamine with iontophoresis," ACS Chem Neurosci. 2010 1(9) p.627-38.